If that is the case you want a midi keyboard/controller, and then something like an Maudio, avid, focusrite, Tascam, etc.
All interfaces come with softwares and the interfaces are pretty much the same thing it just depends on your input and output needs for analog instruments.
No real right or wrong answer. Has more to do with the software preferences. They all come with tons of plugins now so it's just ease of use and flow.